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Scott Welsh, Early State Research Commercialization, College of Agricultural Sciences Fieldstone Innovations

Penn state university

ReMOT Control – a technology for introducing proteins to oocytes

Penn State is working to commercialize a platform technology with applications in invertebrate pest control as well as vaccination and genetic editing of egg bearing food species (poultry & aquaculture). The platform technology (Receptor-MediatedOvary Transduction of Cargo, or “ReMOT Control”) allows for targeting of proteins (i.e. Cas9 or antibodies) into oocytes directly through the female parent. Egg bearing animals represent the majority of all animal species, and oocyte development pathways are well conserved – so this technology could have broad impacts in pest control and food production. The method enables easier and cheaper invertebrate editing – and has been used for the first editing of key disease and agricultural pests such as ticks, mosquitoes, whiteflies, and stinkbugs. Penn State is looking for strategic partners to help develop specific pest control and animal health solutions enabled by our technology.